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Vino 573

About Us

Vino 573 is Hannibal, MO’s premier wine bar, offering a curated selection of fine wines, craft beers, and spirits in a welcoming, stylish setting. Specializing in small bites, gourmet charcuterie, paninis, and flatbreads, we provide both dine-in, carryout, and delivery options to suit any occasion. Enjoy live music and a vibrant atmosphere perfect for relaxing with friends or date night. Experience the best of wine, food, and entertainment at Vino 573—your local destination for good times in Hannibal.

Our Story

Vino 573 is Hannibal, Missouri’s premier destination for fine wine, exceptional food, and unforgettable experiences. Located in the heart of downtown Hannibal, our wine bar was created to offer a welcoming and sophisticated gathering place where friends, families, couples, and visitors can relax, connect, and enjoy life’s simple pleasures.

At Vino 573, we believe great food and drinks bring people together. That's why we've carefully curated a selection of fine wines, craft beers, and premium spirits to suit every palate. Whether you're a seasoned wine enthusiast looking to discover a new favorite vintage or simply searching for a relaxing place to unwind after a long day, our knowledgeable team is here to help guide your experience.

Complementing our beverage offerings is a menu of thoughtfully prepared small bites and gourmet favorites. Guests can enjoy handcrafted charcuterie boards, delicious paninis, flavorful flatbreads, and a variety of shareable appetizers perfect for pairing with a glass of wine or craft cocktail. Our menu is designed to create a relaxed dining experience that encourages conversation, connection, and enjoyment.

What truly sets Vino 573 apart is the atmosphere. Our stylish yet comfortable setting offers the perfect backdrop for everything from casual gatherings and girls’ nights out to romantic date nights and special celebrations. Guests can enjoy a cozy indoor environment while taking in the energy and charm that make Hannibal such a beloved destination.

Entertainment is also an important part of the Vino 573 experience. Throughout the year, we feature live music performances that enhance the atmosphere and create memorable evenings for our guests. Whether you're stopping in for a quick glass of wine, enjoying dinner with friends, or settling in for an evening of live entertainment, there's always something happening at Vino 573.

Convenience is another part of our commitment to exceptional service. In addition to our inviting dine-in experience, we offer carryout and delivery options, making it easy to enjoy your favorite menu items wherever you are.

At Vino 573, our mission is simple: provide outstanding food, carefully selected beverages, and a welcoming environment where guests can relax, celebrate, and create lasting memories. We invite you to discover why so many locals and visitors choose Vino 573 as their favorite destination for wine, food, and entertainment in Hannibal.

Visit us at 209 Center St., Hannibal, MO 63401 or call +1 573-603-0444 to learn more.

Areas Served

Hannibal, MO

What We Offer

Our Specialties include:

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Testimonials

On 7/16/2026 Marie Davis had this to say:
We were actually headed to Brick Oven, not realizing they weren’t open for lunch, and ended up next door at Vino 573. The small charcuterie board was delicious. The pretzel was soft and perfect. I got the mozzarella panini and my husband the brisket panini. Everything was spectacular. They had a strawberry rose slushy special, which was perfect on a hot summer day. Go check them out!

On 7/15/2026 Joshua Don had this to say:
I had an outstanding experience at Vino 573 in Hannibal, Missouri. From the moment we walked in, the atmosphere was warm, inviting, and relaxing. The restaurant has the perfect balance of elegance and comfort, making it a great place for a date night, dinner with friends, or just a quiet evening out. The owners were incredibly welcoming and genuinely kind, taking the time to make everyone feel like family. Their hospitality truly made the experience even more memorable. The food was absolutely phenomenal. The pizza was one of the best I’ve ever had. Every bite was packed with flavor, and you could tell it was made with fresh, high-quality ingredients. The crust was perfectly baked with just the right amount of crispness on the outside while staying soft and chewy on the inside. It had an incredible texture that complemented every topping perfectly. The cheese was rich, fresh, and perfectly melted, creating that amazing stretch with every slice while adding a delicious, creamy flavor that brought everything together. The fresh paninis were just as impressive. They were made with fresh ingredients, served hot, and bursting with flavor. Every bite was perfectly balanced, with delicious fillings and perfectly toasted bread that gave each sandwich an incredible texture. You could really taste the quality of the ingredients, and each panini was satisfying from start to finish. The overall atmosphere made the meal even better. The cozy setting, excellent service, and welcoming environment made it easy to relax and enjoy the evening. You can tell the owners genuinely care about their customers and take pride in creating an exceptional experience. If you’re in Hannibal, Vino 573 is an absolute must-visit. Between the incredible pizza with its perfect crust and delicious cheese, the amazingly fresh and flavorful paninis, the wonderful atmosphere, and the genuinely kind owners, this is easily one of the best dining experiences I’ve had. I can’t wait to come back and highly recommend it to anyone looking for outstanding food, exceptional hospitality, and an unforgettable experience.

On 7/14/2026 Jenny Webb had this to say:
New wine restaurant serving a wide variety of wimes, house made paninis/wraps, pizza, charcuterie boards, and other light options. Bottled beer available. Former bank vault outfitted as a cigar humidor. Llve music performers in the vault room on some.week nights and weekends.

On 6/28/2026 Evan J. had this to say:
Highly Recommend! Vino 573 in Hannibal is a hidden gem! The cozy, welcoming atmosphere is perfect for date nights or casual evenings with friends. The wine selection is fantastic -- great variety by the glass and bottle, with knowledgeable staff who really know their stuff. The food is delicious too -- fresh, flavorful small plates and entrees that pair perfectly with the wines. My family and I had an excellent experience from start to finish. If you're in Hannibal, don't miss this spot! 10/10 -- we'll definitely be back.

Contact Us

Vino 573
209 Center St Hannibal, MO 63401
Phone: (573) 603-0444
Email: info@vino573.com

Payment Types Accepted

Debit & Credit Cards, Tap to Pay, Cash

Our Hours

Monday: 11:00 AM - 10:00 PM
Tuesday: 11:00 AM - 10:00 PM
Wednesday: 11:00 AM - 10:00 PM
Thursday: 11:00 AM - 10:00 PM
Friday: 11:00 AM - 12:00 AM
Saturday: 11:00 AM - 12:00 AM
Sunday: 12:00 PM - 8:00 PM

FAQ

Do you offer dine-in service?
Yes! Guests can enjoy our full menu and beverage selection in our welcoming wine bar atmosphere.
Do you offer carryout and delivery?
Absolutely. We offer convenient carryout and delivery options for many of our menu items.
Do you have live music?
Yes! We regularly feature live music and entertainment for guests to enjoy.
What kind of food do you serve?
We specialize in gourmet small bites including charcuterie boards, paninis, flatbreads, and other shareable favorites.
Do you serve more than wine?
Yes. In addition to fine wines, we offer craft beer, premium spirits, and a variety of beverage options.

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